T-ALL PDXs were treated with vehicle, ATO (2.5 mg/kg), MTX (5 mg/kg for BCP-ALL
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Bacteriostatic water is sterile water containing 0.9% benzyl alcohol (9mg per ml) as a bacteriostatic preservative
Amylin analogues are heavily studied for their capacity to slow the rate of gastric emptying, thereby regulating the influx of nutrients into the duodenum
10.1016/j.nbd.2006.08.004 Neurobiol
Indeed, melatonin is highly permeable to cell membranes and easily crosses the bloodbrain barrier 51 , ensuring a good therapeutic profile for brain diseases, and is also able to accumulate into mitochondria, probably via GLUT/SLC2A and PEPT1/2 carriers 52,53