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Specifically, in 3D bronchial tissues exposed to cigarette smoke, levels of key PPP intermediates (e.g., 6-phosphogluconate, erythrose-4-phosphate) are significantly elevated, while the activity of G6PD, which is the rate-limiting enzyme of the PPP, is enhanced

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-cryptoxanthin, a main kind of xanthophyll, is abundant in Satsuma mandarin orange ( Citrus unshiu )