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Synthesis of aryl-fused bicyclo[3.1.1]heptanes and validation as naphthyl bioisosteres

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Following incubation, the wells are washed and then incubated with Biotinylated Anti-Glutathione Synthetase Antibody, which binds the captured Glutathione Synthetase present in each well

Schmitt R, Melk A

This finding suggests that GSH supplementation may help to shift the balance towards a more reduced environment, potentially protecting against oxidative damage