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These studies allow researchers to investigate how peptide-mediated protein interactions influence regulatory pathways inside the cell

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One of MOTS-C's downstream effects is increasing intracellular NAD+ utilization the mitochondria are running harder, so they're consuming more of the NAD+ pool

Nature (1997) 387(6636):91721.10.1038/43206 127 HiltonDJRichardsonRTAlexanderWSVineyEMWillsonTASpriggNSet alTwenty proteins containing a C-terminal SOCS box form five structural classes

PLoS One (2016) 11(5):e0156218.10.1371/journal.pone.0156218 77 OSheaJJGadinaMChenXM