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Binds extracellular and exchangeable copper(II) ions with high affinity, facilitating copper delivery into cells and enhancing the action of copper-dependent enzymes necessary for extracellular matrix synthesis and antioxidant defenses 2

Two independent levers pulled simultaneously

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Smoking is perhaps the most damaging, as it dramatically reduces blood flow to the already poorly-vascularized rotator cuff tendons

An injection bypasses that route