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Borenstein, 2009):Where SD change is the SD of the mean changes from baseline, SD baseline is the SD of the pre-test, SD final is the SD of the post-test, and r is the correlation between the baseline and final measurements

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However, the researchers noted that individual responses could vary, and more research is needed to fully understand this relationship

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Participants were then randomized into three groups: staying on their maximum dose, tapering down to a 5 mg dose, or placebo