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Cell lines, culture conditions, transfection and infection The Human SimpsonGolabiBehmel syndrome (SGBS) cell line was kindly supplied by Martin Wabitsch (University of Ulm, Germany) 45 and authenticated as preadipocytes based on their response to adipogenic cues (cocktails) and the expression of adipogenic marker genes
for KPV, concentrations of 15 mg/mL are common in published protocols
Less Common Joint pain or stiffness Numbness or tingling These typically resolve with continued use or dose adjustment
Notably, Brusatol, a natural NRF2 inhibitor, enhances the binding of KEAP1 to NRF2, promotes NRF2 ubiquitination, and accelerates its proteasomal degradation, thereby suppressing NRF2-driven antioxidant function and sensitizing cancer cells to oxidative stress
2022 Mar
