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These results supported the hypothesis we previously proposed 8 that once the metabolic activity of yeast cells is temporarily disrupted by environmental stresses, the central carbon metabolism of C

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This is accompanied by elevation in the levels of various pro-inflammatory cytokines and chemokines, including TNF-, IL-1, IL-6, IL-8, RANTES (CCL5), and Monocyte Chemoattractant Protein-1 (MCP-1) [65,66,67,68]

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Chronic or heavy alcohol consumption increases CYP2E1 activity, which in turn elevates NAPQI formation from acetaminophen metabolism