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Most patients notice appetite changes within the first 12 weeks
Yang, J., Ueharu, H
Ozempic Legs: Why GLP-1 Weight Loss Changes the Appearance of the Legs and Thighs Date Written by James Bartholomeusz Revised by Martha Viera, MD Rapid weight loss from GLP-1 medications can "deflate" the legs, making cellulite and skin laxity more visible as fat pads shrink and muscle mass declines
Likewise, Wenjing et al
That averages out to a 5% weight loss without even utilizing the maximally tolerated dose
This finding positions GLP-1 medications as essential tools alongside traditional CVD therapies
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