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Andrew: When you're in this whole-body systemic pain and discomfort and you getting that saliva, I'm sensing it now, I have a distinct memory of this, for people that get seasick, you think about being on a boat and walking back and forth get a little nauseous, someone would walk in the room and you're like, "God, why are they walking like that?" It's your sense of pain

We assessed the primary endpoint with an independent t test

This happens when the lower oesophageal sphincter, a ring of muscle that normally prevents acid from travelling upwards, doesnt close properly

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Since these tumors are very aggressive, high local tumor burden and regional lymph node metastases are often identified at the time of initial diagnosis

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