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Upon the upregulation and activation of Nrf2, the heterodimers of nuclear Nrf2 and small Maf proteins form to recognize antioxidant response elements (AREs), and then recruit key factors for transcription of Nrf2 target gene including HO-1 (Hayes et al., 2010)

Reconstitution and Injection Technique Standard Reconstitution Protocols Standard reconstitution for 50 mg vials uses 3 mL bacteriostatic water yielding approximately 16.7 mg/mL concentration

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