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Liver-mediated metabolic processes, including phase I and phase II metabolism, which may alter drug activity or promote its excretion

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1 Introduction Cancer is a global health concern, with an estimated 19.3 million new cases and almost 10 million deaths reported in 2020 (Sung et al., 2021)

Any references to tissue, vascular, or gastrointestinal models are provided only for research context and do not imply therapeutic or clinical use