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An initial 4-month dose escalation period evaluated different doses (120, 240, and 360 g) and administration frequencies (two or three times daily) for pramlintide and was followed by an 8-month extension of the pre-assigned pramlintide treatment regime

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Novo Nordisks failure to disclose information that they possessed regarding the causal association between the use of GLP-1RAs and the risk of developing necrotizing pancreatitis, rendered the warnings for Ozempic inadequate. Necrotizing pancreatitis occurs when part of the pancreas dies due to inflammation or injury

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