As acetaminophen detoxification proceeds in this fashion, glutathione, a ubiquitous cellular antioxidant, eventually becomes depleted (Moyer 2011), and NAPQI can no longer be sufficiently detoxified (James 2003)
Filloux A, Davies JC
The right next step depends on the reader's evidence, safety, cost, access, and provider-review needs
Patients whose only complaint is weight and who have no secondary concerns about skin, hair, inflammation, or tissue quality are better served by optimizing their GLP-1 protocol, adding resistance training, and addressing nutrition rather than adding a peptide that doesnt directly address their primary goal
It also seems to have prevented the down-regulation of the IGF-I receptor and possibly inhibited apoptosis
Hoffmann-La Roche Ltd