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Understanding your genetic profile may help contextualize why certain metabolic challenges feel more pronounced or why your response to lifestyle changes differs from others
doi: 10.1186/s12944-025-02563-0 78 LiHXWangSQLianZXDengSLYuK
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Astragaloside IV can inhibit the phosphorylation of the mTOR signaling pathway, downregulate the Bcl-6 transcription factor in Tfh, and upregulate the CTLA-4 expression in T follicular regulatory cells (Tfr), thereby reshaping the Tfh/Tfr balance to reduce the release of pro-inflammatory factors such as IL-21