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Acute renal injury, also known as acute renal failure (ARF), is characterized by rapid decline in kidney function 2,3

It was first isolated in 1973 when researchers noted its powerful cell regenerating capacity in experiments with liver cells

However, before deciding to go forward with these enzymes, the pathway was analysed by Equilibrator [3] to observe the feasibility and potential bottleneck of the whole cascade, along with the free energy analysis under physiological conditions

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In wild-type S

Unfortunately, data is inconsistent among these studies, likely due to the different methodologies used between studies, making it difficult to provide firm conclusions