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Astrocytes contribute to the stability of the neuronal microenvironment [41] and react to tissue injury by increasing the expression of GFAP, an intermediate filament protein expressed by astrocytes [42, 43]

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Given that dulaglutide 1.5 mg is more efficacious than dulaglutide 0.75 mg, and that the two doses are associated with the same annual cost, once-weekly semaglutide 0.5 mg can be presumed to have a lower cost of control than dulaglutide 0.75 mg for all endpoints in Spain

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