GLP-1 receptor activation produces appetite suppression through hypothalamic signaling, slows gastric emptying to promote prolonged feelings of fullness, improves insulin secretion in response to meals, and reduces glucagon secretion that would otherwise raise blood sugar levels
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GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial
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By staying proactive and patient-centric, providers can help patients continue their weight-loss journey safely and effectively. Patients may feel frustrated, confused or anxious about losing access to medications that were working for them
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