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For those who use B12 injections, timing is not a concern

Here is the honest hea Research-use-only reference

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Individuals Taking Certain Medications Some drugs, like metformin or proton pump inhibitors, can interfere with B12 absorption

Based on the available evidence, cagrilintide appears to have a more favorable body composition profile, though the magnitude of difference between the two compounds remains to be determined through direct comparison studies