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it predates modern trial standards for the adult uses now marketed

10.3389/fphar.2022.897669 10 HuangX.ChangL.LuY.LiZ.KangZ.ZhangX.et al (2020)

For information on the use of these drugs to treat diabetes during pregnancy, in children and adolescents, and for the prevention of diabetes see other Endotext chapters (2-4)