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There was no significant change in BMI within the exenatide group at 12 weeks, indicating that the effect on intracranial pressure was not driven by reduction in body weight, but likely by direct effect of exenatide to modulate intracranial pressure at the choroid plexus

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It works through AMP-activated protein kinase (AMPK) activation, which actually shares some mechanistic overlap with ketosis

The Ethical Questions GLP-1 drugs represent a genuine medical breakthrough for many people struggling with obesity and metabolic disease

The compound was well tolerated with no evidence of genotoxicity, indicating its potential as a therapeutic agent for type 2 diabetes and obesity in humans

Each of the three receptor pathways it activates contributes a different piece to the overall weight loss effect