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[14] [39] In December 2025, the FDA approved an oral version of semaglutide for weight management, using the same brand name (Wegovy) as the injectable version

But what is it, exactly

Retatrutide targets three hormones to aid weight loss, unlike other weight loss medications that target one or two

This is an ideal time to assess whether your current approach is working or whether adjustments to diet, activity, or dose timing would be beneficial

Adherence could also be a greater issue with combination therapy versus a single/linear therapy approach because the more drugs a patient needs to take each day the greater the potential for poor treatment adherence [52]

Jul 2012;27(5):335-42