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Oncologist 17, 7279

doi: 10.3389/fendo.2011.00032 84 GarmesHMCastilloARMonte AlegreSde SouzaALAtalaYBZantut-WittmannDE

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Oxidative stress arises when there is an imbalance between oxidant generation and antioxidant capacity, leading to the accumulation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), ultimately resulting in cellular injury and dysfunction 1