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5-Amino-1MQ acts as a potent activator of AMP-activated protein kinase (AMPK), a crucial enzyme involved in fat cell metabolism and muscle tissue regeneration

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The investigators attributed the angiogenic effect to upregulation of vascular endothelial growth factor receptor 2 (VEGFR2) and activation of the Aktendothelial nitric oxide synthase (eNOS) signaling pathway