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Given the limited therapeutic benefits associated with NAC in cancer treatment, and the number of other antioxidants shown above to help reduce the toxicities of these two chemotherapeutic agents, there appears little reason to consider NAC a first-line adjunct with either agent

And one thing is consistent

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Similarly, caution should be exercised in patients with a family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2

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Because consumers considered the drugs a cheaper, easier to access alternative, interest in compounded treatments skyrocketed