Side-effect context matters for people with diabetes, dehydration risk, kidney disease, gallbladder disease, severe reflux, gastroparesis (delayed stomach emptying), or a history of pancreatitis
doi: 10.12998/wjcc.v4.i7.155 171 MuY.McManusD
When activated, Nrf2 disassociates from its repressor protein KEAP1 that reacts with oxidative radicals, translocates to the nucleus, binds to antioxidant response element and induces the transcription of defensive genes
Adipocyte-expressed SIRT3 manipulates carnitine pool to orchestrate metabolic reprogramming and polarization of macrophages
Therefore, the decrease in penile tissue DHT, which has been reported to occur during sexual maturation,20 may be a factor contributing to the AR reduction and penile growth arrest, despite the increase in circulating DHT
Back to Journals Diabetes, Metabolic Syndrome and Obesity Volume 19 GLP-1 Agonists in Adolescent Obesity: A Narrative Review of Single, Dual, and Triple Agonists Authors Abid M, Sheikh KS, Ahmad MS, Jiang H Received 19 January 2026 Accepted for publication 17 March 2026 Published 12 June 2026 Volume 2026:19 566414 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Donald McClain Mahroz Abid, 1 Khizer Sohail Sheikh, 1 Muhammad Shahbaz Ahmad, 2 Hongwei Jiang 1 1 Department of Metabolism and Endocrinology, Endocrine and Metabolic Disease Center, The First Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Peoples Republic of China