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Dopamine multilocus genetic profile influence on reward network in chronic insomnia disorder with depression

Understanding this helps contextualize the temporary worsening some researchers experience

doi:10.1210/jcem.86.8.7747 Benvenga S, Amato A, Calvani M, Trimarchi F

A recent investigation revealed that the expression of VRK2 was upregulated in response to ROS signals, while the link between VRK2 and metabolic rewiring remains obscure [18].In this study, we tried to explore the effects of VRK2 on the rewiring of metabolic networks and identify metabolic vulnerabilities resulting from VRK2-driven metabolic reprogramming

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Thus, omega-3 PUFA-derived SPMs effectively balance the neuroinflammatory and pain processes in the interaction between glial cells and neurons (18)