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These include pathways involved in cell migration, collagen formation, and extracellular matrix organization

Macrophages and nociceptor neurons form a sentinel unit around fenestrated capillaries to defend the synovium from circulating immune challenge

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For a loading protocol of 2.5 mg twice per week, reconstituting with 2 mL gives 2.5 mg/mL, so each 2.5 mg dose is 100 units (the full syringe)