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[14][15] Early KP lesions, characterized by small keratinous plugs and no hair shaft abnormalities, showed atrophic sebaceous glands

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High-dose use While trials have tested up to 1200mg/day (even as high as 2400mg/day) and illustrated safety, some report higher rates of gastrointestinal side effects, dizziness, and skin reactions at these levels.14 28 38 Additionally, these higher doses are often short-term (35 weeks) and used under clinical supervision

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