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[1] Peptides and Gut Microbiome The gut microbiome is a complex and dynamic ecosystem composed of bacteria, viruses, fungi, and other microorganisms that interact closely with host physiology

Those most at risk include vegans and vegetarians, people with digestive conditions such as Crohn's disease, coeliac disease or IBS, those taking long-term metformin or proton pump inhibitors, older adults whose ability to absorb B12 through the gut declines naturally with age, those with pernicious anaemia, and anyone with a history of chronic alcohol use

The conversion of spermine to spermidine generates not only spermidine but also H 2 O 2 and 3-aminopropanal (3-AP)

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