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Large doses of vitamin D can be harmful, even though there may not be immediate symptoms of toxicity

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PLOS ONE (2015)

The beyond-use date (typically 90 days from compounding) is an absolute cutoff

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We next repeated this experimental paradigm in Gipr hypo-KO and Gipr hypo-GFP mice, combining the initiation of HFD with a combination of LIRA (or VEH) alone or LIRA (or VEH) plus GIPR antagonist peptide (GIPR-antag)