Composite endpoints that include metabolic endpoints, validated psychological measures such as the PHQ-9 for depression, BES or measures of quality of life can better reflect improvements in both physical and mental health [41]
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EBioMedicine 21 , 2128 (2017)
L-carnitine also showed hepatoprotective and renal protective effects suggesting liver/brain and kidney/brain axes as possible mechanisms for its neuroprotective effects
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As a pharmaceutical professional, I see this reshaping not just prescribing patterns, but how we counsel patients, manage formulary decisions, and think about long-term weight management support at the pharmacy level