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This signaling cascade subsequently elevates ACSL4 expression, driving lipid peroxidation and ferroptosis through the ACSL4/lysophosphatidylcholine acyltransferase 3/arachidonate lipoxygenase 15 axis, as demonstrated in both in vitro and in vivo models of severe acute pancreatitis (114)
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TMX-treated rats had significantly lower activities of CAT ( F (3, 16) = 137.80
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Nutrition, 24 (2), 140-147
In this study, SARS-CoV-2 infection up-regulated expression of genes enriched in signaling pathways relevant to inflammatory response (such as NF-B and NOD-like receptor signaling pathway) (102)
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