N Engl J Med 2016;375:19:1834-1844
The implications are far-reaching
The patent holders own foundational disclosure does the work
Claiming the patch is completely painless also seems unrealistic, as applying and removing patches with microneedles, however small, will likely cause at least minor and transient discomfort
Fried foods (french fries, fried chicken, donuts) Fatty cuts of meat Full-fat dairy products Creamy sauces and gravies Fast food burgers and pizza Acidic Foods These can irritate an already sensitive esophagus: Citrus fruits and juices (oranges, grapefruits, lemons) Tomatoes and tomato-based products (pasta sauce, ketchup) Vinegar-based dressings Spicy Foods Hot peppers, hot sauces, and heavily spiced dishes can trigger heartburn in many people
Evening (8-9pm): Optional small protein if hungry