The magnitude of these benefit exceeded those expected from improved glycemic control more generally
The Risks, Side Effects, and Why Careful Dosing of GLP-1 Matters GLP-1 medications like Ozempic, Wegovy, Zepbound, and Mounjaro have helped many people lose weight, Disclaimer: This blog post is for informational purposes only and should not be considered medical advice
In animal studies, GLP-1 receptor agonists have been associated with thyroid C-cell tumours, though this finding has not been established in humans
However, in the late 20th century, scientists discovered the "Incretin Effect." They noticed that oral glucose triggered a much higher insulin response than intravenous glucose
Risk is highest during the initial titration phase and subsequent dose increases, particularly in vulnerable populations such as older adults or those with pre-existing conditions
One recent randomized control trial split participants into an exercise group, a GLP-1 group, and a combined group (7)
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