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These data provide strong evidence that oxidative stress/GSH depletion induced by SFN inhibits STAT3 activation in primary human T-cells connecting SFN treatment to T H 17-skewing of T-cell responses

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Retrieved May 6, 2025, from MedIndia

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Nrf2 mainly regulates ferroptosis across three dimensions: iron metabolism, lipid metabolism, and intermediate metabolism (Fig

In LPS-induced inflammatory mice, L-theanine treatment reduced the acute liver injury by inhibition of the concentrations of ALT and AST, the level of hepatic total superoxide dismutase (T-SOD), and malondialdehyde (MDA) ( With regard to kidney protection, in the doxorubicin (DOX) induced acute nephrotoxicity rat models, it was found that the treatment with L-theanine could attenuate the decrease of creatinine clearance, inhibit the production of lipid peroxidation in the kidney, and inhibit the reduction of glutathione content and SOD activity after DOX administration (90)