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Despite the small sample size (only 10 patients), the observed benefits suggest that GLP-1RAs could have a therapeutic role in PsA through inflammation reduction, similar to what had been observed in PsO (61)

Bloating Bloating is another one of the most common semaglutide side effects

Importantly, HDL cholesterol (the protective kind) often remained stable or increased slightly, creating a more favorable overall cholesterol profile

The combination group showed 1.3 kg greater fat mass reduction measured via DEXA scan, though the difference did not reach statistical significance (p=0.08)

Unlike small molecules, peptides are detectable only at the margins, rendering them acutely sensitive to physiological fluctuations that would have a negligible impact on conventional drugs

Researchers analyzed over 40,000 posts across TikTok, Reddit, and YouTube regarding GLP-1 medications