Ongoing Phase 2 study of topical GHK-Cu gel for acute skin-wound healing
In wild type mice, MOR recovery was slow after ME-induced desensitization (approximately 60 minutes), similar to results reported earlier for locus coeruleus neurons from rat (Osborne and Williams, 1995
Other studies have reported that efficient desensitization of MOR by highly efficacious agonists persists when GRK phosphorylation, arrestin binding, or endocytosis are disrupted
Myasthenia Gravis is treated with immunosuppressants to decrease the production of antibodies that destroy nAChRs as well as with acetylcholine esterase inhibitors [AChEIs] that prevent the breakdown of acetylcholine, a nAChR agonist, to increase its level in the synapse
However, it is crucial to inform your healthcare provider about all the medications you are currently taking to ensure there are no contraindications or interactions
Common Side Effects Injection site reactions account for the vast majority of reported side effects