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Developmental fluoxetine exposure affects adolescent and adult bone depending on the dose and period of exposure in mice

ELS, MES, IJW, YT, NRS, TMB, JPRP, JDG, JSM, RMS, RGP, GAN, RS, TBR, AK, RD, TS, PB, and IL-P are site investigators on the study, receive no compensation from the Sponsor and declare no conflicts relating to the study

A good stack should feel like a support system, not like a second job

doi: 10.1007/s00018-005-5121-4

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Biomarkers tested Beyond behavioral testing, the researchers conducted extensive analysis of brain tissue, measuring various crucial markers: [1] Brain-derived neurotrophic factor (BDNF) Key neurotransmitters (acetylcholine, dopamine, GABA) Antioxidant markers (catalase, glutathione) Beta-amyloid levels Cyclic GMP This comprehensive approach allowed the research team to not only observe behavioral outcomes but also understand the underlying neurochemical changes driving these effects