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Eloralintide selectively and potently activates AMY1R with much lower activity at CTR and reduced activity at AMY3R, consistent with focused amylin-pathway agonism enhance satiety and reduced caloric intake

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Patients may notice return of hyperglycemia symptoms such as increased thirst, frequent urination, and fatigue

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Its integration with zebrafish models facilitates large-scale drug screening with minimal sample consumption and enables systematic analysis of dose-response relationships and compound synergies through controlled concentration gradients and combinatorial strategies

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