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Disruption in GSH homeostasis has been linked to initiation and progression of neurodegenerative diseases

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Biochemistry 38(42):1378713794 Dekker LV, Parker PJ (1997) Regulated binding of the protein kinase C substrate GAP-43 to the V0/C2 region of protein kinase C-delta

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The serum-induced increase in p53 ubiquitination was blocked by a PI3K inhibitor, suggesting that phosphorylated Akt enhances the ubiquitination-promoting function of MDM2, determining reduction of the p53 protein

Within laboratory settings, Melanotan 2 is studied for its interaction with melanocortin receptors