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Scientists at the University of Nottingham, UK, have conducted a short-term intervention study to explore the effectiveness of a very low-calorie diet and Semaglutide, individually and in combination, in reducing body weight and controlling blood glucose in patients with type 2 diabetes

The tradeoff is that semaglutide generally produces slightly less weight loss than tirzepatide in clinical comparisons, as tirzepatide is a dual GIP/GLP-1 agonist while semaglutide only targets GLP-1

It allows the body to readjust without putting it through the stress of withdrawal symptoms

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The absence of hunger, gastric emptying delay, food aversion, reduced interest in eating these are the lived goals of the restrictive eating disorder

Type 2 diabetes in adults: management Blood glucose management chapter (NG28)