Heartburn/Reflux
Common Examples: Warfarin Digoxin Lithium Phenytoin Theophylline Insulin Tacrolimus Vancomycin Why are they important
Note that there are important differences between products: Ozempic (for diabetes) is a multi-dose pen while Wegovy (for weight management) comes as single-dose pens with different handling requirements
Potential considerations include: Gastrointestinal sensitivity during therapy initiation
Proteostasis resilience: a systems-level perspective Together, these functional, spatial and adaptive properties define what can be conceptualized as proteostasis resilience, the capacity of cells, tissues and organisms to sustain proteome integrity despite acute or chronic stress
Abel J, Goldmann O, Ziegler C, Holtje C, Smeltzer MS, Cheung AL, Bruhn D, Rohde M, Medina E (2011) Staphylococcus aureus evades the extracellular antimicrobial activity of mast cells by promoting its own uptake