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We previously demonstrated that growth attenuation of rv1127c in propionate is rescued by the addition of either vitamin B 12 or acetate (Basu et al, 2018), data that phenocopies Mtb mutants lacking MCC enzymes (Lee et al, 2013), thus supporting an unexpected role for Rv1127c in the MCC (Borah et al, 2021)

Nutrition 26:112119 Kandil S, Brennan L, McBean GJ (2010) Glutathione depletion causes a JNK and p38 MAPK -mediated increase in expression of cystathionine--lyase and upregulation of the transsulfuration pathway in C6 glioma cells