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89 The ECG (e.g., right-axis deviation, P-pulmonale, RV hypertrophy) and chest X-ray (PA enlargement, right ventricular dilation) findings lack sensitivity in the early disease stage

High blood alcohol concentrations activate the CYP2E1-induced oxidative pathway, resulting in the overproduction of ROS and the depletion of endogenous antioxidants [31]

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Oxidative stress in chronic kidney disease