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Mechanistic analysis using endocytosis pathway inhibitors indicated that PTX-CDs predominantly traverse the BBB via macropinocytosis, highlighting the involvement of energy-dependent vesicular uptake mechanisms in BBB translocation [148]

Knowledge in this respect is important since oral administration should provide these patients with greater autonomy, improve patient satisfaction with treatment, and reduce treatment costs

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These repeated audits did not allow for GPs to treat patients as individuals