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In GLP-1 protocols (Mounjaro / Ozempic), it's used as GI support for nausea, discomfort, or reflux

Massart, J., Begriche, K., Moreau, C

The lack of blood supply to the heart may cause heart attacks and the lack of blood supply to the brain accelerates the development of dementia and may lead to strokes

Immunogenicity and other problems associated with the use of biopharmaceuticals

12 Journal of Chromatography B (PubMed)Quantification of TB-500 metabolites and screening of wound-healing activity (prodrug hypothesis)

While animal studies extending to 6 weeks have found no concerning signals, humans using the peptide are essentially participating in uncontrolled self-experimentation regarding long-term outcomes