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New Engl J Med 1995;332:158993.10.1056/NEJM199506153322401CrossRefGoogle ScholarPubMed Anderson, G L, Limacher, M, Assaf, A R, Bassford, T, Beresford, S A, Black, H, et al

Beyond appetite control, these medications also reduce chronic inflammation , improve lipid profiles, lower blood pressure, and provide meaningful cardiovascular protection making them true metabolic therapies, not just weight loss drugs.

Storage outside this range can compromise the medication's ability to activate appetite-suppressing pathways and reduce glucose-dependent insulin secretion

You start with a 2.5-milligram dose and increase to 5 milligrams after a month

P.FinkH.FriedlandK.GauthierS.et al (2019)