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Interview Studying how genomes stay intact July 20, 2026 Patrick OBrien discusses DNA repair, enzyme evolution, scientific publishing and mentorship, reflecting on the curiosity-driven questions that shaped his career and his approach as a JBC associate editor

Adeno-associated virus was used to target hippocampal astrocytes in an APPP/PS1 mice for inducing VIVIT expression, which inhibits reactivity via the calcineurin pathway

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Though his finished art is famously slick and often icy-cold, it masks an unconscious hornets nest of sweat-soaked neuroses and untidy thoughts (Exhibit A being the aforementioned repeat appearances by female derrieres)