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Top-degree targets underwent molecular docking with AutoDock Vina ( visualized in PyMOL ( Secondary intersection analysis identified shared PFAS/folate-disease targets to explore folates potential modulation of PFAS-induced lipid disorders

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To obtain cell surface proteome lists for T cell, CAR-T cell and TCR-T cell monocultures (grown in the absence of tumor cells), we applied a log 2 -transformed fold change cutoff with a 5% false discovery rate (FDR), defined by the retention of cytosolic and nuclear proteins, which should not be labeled by LaccID (Supplementary Fig